Healthy plants are the foundation of life on earth, and plant diseases and pests are major threats to global food production and security. The UK attaches great importance to plant safety management and has started laying out relevant policies earlier, making good progress in building a risk prevention and control system. In this study, we conducted an in-depth analysis of the UK's experience and practices in strategic planning, governance systems, institutional construction, technology research and development, and international cooperation using literature review, analysis, synthesis, and comparative research. The UK government has incorporated plant biosecurity into its national security strategy, coordinated the system of plant biosecurity organizations, developed internationally advanced safety systems, constructed a plant supply chain with biosecurity guarantees, promoted deep integration of industry, academia, and research, and vigorously developed national science, which is an important reference for China's biosecurity construction.