【Aim】 Insect-resistant and herbicide-tolerant maize MON87411 is a maize event developed by Monsanto Far East Co. Ltd. using agrobacterium mediated transformation through recombinant DNA techniques. It has obtained a safety certificate for genetically modified agricultural organisms imported to China as raw materials for processing. Establishing a quantitative detection method for the event to meet the requirements of biosafety compliance is necessary. 【Method】 Primers and TaqMan probes were designed based on the flanking sequence information of maize MON87411. After primer screening, specificity detection, PCR system optimization, standard curve establishment, accuracy and precision detection, limit of detection (LOD), limit of quantification (LOQ) detection, and droplet digital PCR validation were performed. 【Result】 The results showed that the method could specifically and quantitatively detect the components of maize MON87411, with a LOD of 10 copies and a LOQ of 40 copies. The values of the tested samples were accurate, and the results were consistent with those of droplet digital PCR. 【Conclusion】 The method provides a new detection method for accurately quantifying the new genetically modified maize MON87411 and provides effective technical support for biosafety supervision.