[Aim] Identification of appropriate indicators to develop a risk assessment method for biological invasion of exotic farmed fishes and to propose countermeasures for its prevention and control.[Method] The study analyzed the overall process of invasion, evaluated the damage, investigated the biological characteristics of typical invasive exotic farmed fish, and indicated their invasion from three aspects using literature data, viz., adaptability, reproduction capacity, and diffusion ability; indicated the ecological impacts in terms of both biological and environmental impacts; natural factors and human factors are considered to indicate the invasibility of environment, and the evaluation system was developed using these factors as a framework.[Result] Twenty indicators were screened to develop a risk assessment method for biological invasion potential of exotic farmed fishes, the application of which was further validated with the help of an example. The countermeasures for prevention and control of the biological invasion risk of farmed exotic fishes were proposed from four perspectives:laws and regulation, scientific research, governance technology, and public participation.[Conclusion] Prevention and management of invasive species is a systematic process. We should not just emphasize on economic gains while ignoring ecological hazards, nor can we unilaterally increase the risk of invasion of such farmed species. The key to successful scientific management and control is to improve strategic approaches, strengthen risk assessment, develop prevention and control methods, and promote public participation. Through such actions, the exotic fish farming business may reap economic benefits while maintaining strict control of invasive species and may minimize their potential ecological impact.