[Aim] The impact of genetically modified crops on non-target insects is an important part of environmental safety assessment of genetically modified crops. To study the effect of Cry2Ab protein on the Propylaea japonica, it is of great significance for the environmental safety evaluation of genetically modified crops.[Method] Adding the Cry2Ab protein to the sucrose solution, study the effects of Cry2Ab protein on the developmental duration, adult body mass, sex ratio and amino acid type and content of the Propylaea japonica.[Result] Compared with the control group fed with sucrose water, there was no significant difference in developmental duration, adult body mass, sex ratio, amino acid species and contents in Propylaea japonica by Cry2Ab protein feeding.[Conclusion] The Cry2Ab protein had no significant effect on the individual development and metabolism of the Propylaea japonica.