[Aim]In order to control rice water weevil overlarge areas, a new ultra-low volume spraying technology was developed, and tested under the special environmental conditions of a Xinjiang desert oasis.[Method]Selecting and optimizing experiments including pesticides, spray rates, adjuvants and spray equipment were carried out by using a remote-controlled multi-rotor plant protection sprayer as pesticide application machine and conventional pesticides for controlling rice water weevil whose efficiency was higher than 90% as the first agents.[Result]After pesticide application for 3 d, 7 d, 14 d, and 21 d, the proportion of plots where the density of insect populations was higher than the damage thershold was 35.71%, 21.43%, 35.71%, and 78.57%, respectively. The best control effect (93.43%) was achieved by 30% chlorfenapyr and thiamethoxam with the dosage of 187.5 mL·hm^-2 after 14 d of pesticide application. After pesticide application for 21 d, the control effect by Beauveria bassiana with the dosage of 3000 mL·hm^-2 was the highest(84.65%). The spray rate of each agent was positively correlated with the control effect. In addition, when UAV spray was used to control rice weevil, the average control effect of adding adjuvants could increase 22.29%-28.49%.[Conclusion]To achieve precision while minimising pesticide use, it is recommened that 30% chlorfenidil and thiamethoxam SC and 14% chlorfenidil and high chlorofluorocarbon CS were the first choices against the rice water weevil. In the early and middle development of the rice water weevil population, low-concentration applications were sufficient.