[Aim] Chouioia cunea is the main natural enemy of the invasive pest Hyphantria cunea. Molecular expression analyses of different tissues and both sexes of this pest show that eight OBPs are exclusively or primarily expressed in female antennae. However, the specific structure and function of these OBPs are still unknown. In this study, CcOBP1, which mainly expressed in the antenna of female C. cunea, was selected to study its functions by molecular docking technique.[Method] The best suitable 3D model of the CcOBP1 was obtained by Swiss-Model. The 3D structure of 11 ligands such as γ-butyrolactone, dimethyl phthalate and naphthalene were downloaded from Pubchem. Molecular docking was done using maestro 10.2 software from Schrodinger suite 2015-2.[Result] Among the 11 kinds of volatiles of H. cunea, three small molecules could bind to OBP1:γ-butyrolactone, dimethyl phthalate, and naphthalene.[Conclusion] The Odorant binding proteins CcOBP1 has a good binding affinity with γ-butyrolactone, dimethyl phthalate and naphthalene, and the function of CcOBP1 may be related to the repellent effect of C. cunea. These results may contribute to the understanding the olfactory molecular mechanisms of C. cunea.