[Aim] The banana sigatoka disease is an important disease threatening banana production. Currently, chemical control is the most effective method. In order to assist appropriate application rates, chemical control experiment of banana sigatoka disease was carried out in the field in 2015-2016.[Method] Five treatments were designed including 3 concentrations of 22.5% picoxystrobin SC (125 mg·kg^-1, 150 mg·kg^-1 and 187.5 mg·kg^-1), 250 g·L^-1 pyraclostrobin EC (125 mg·kg^-1) and the blank control (sprayed 3 times). We evaluated the responses by counting the normal vs. diseased leaves, disease severiaty after 12-13 days, and calculating the average disease index and control effect.[Result] The control effect of 22.5% picoxystrobin SC (125 mg·kg^-1, 150 mg·kg^-1 and 187.5 mg·kg^-1) on the banana sigatoka disease was 64.70%, 68.16% and 71.29%, respectively, in 2015 and 68.44%, 72.36% and 76.29%, respectively, in 2016. In addition, during the experiment period, no damage was observed in the young leaves of the banana, and the leaf growth was normal.[Conclusion] 22.5% picoxystrobin SC is an excellent fungicide for controlling banana sigatoka disease, and it is safe to banana, so it can be popularized in banana production.