[Aim] In recent years, American sorghum has been imported into China in large quantities, but there is no research about seeds of weeds carried with the American sorghum. According to analysis of the intercepted seeds from American sorghum containers we can provide evidence for the need of quarantine and follow-up supervision of CIQ.[Method] Through the study of seeds intercepted in imported American sorghum from 2014 to 2016, their status as weeds were recorded.[Result] A total of 106 species of weeds belonging to 19 families were intercepted from the imported American sorghum by Huangpu Entry-Exit Inspection and Quarantine Bureau and Nansha Entry-Exit Inspection and Quarantine Bureau. The list included Gramineae (27 species), Asteraceae (14 species), Euphorbiaceae (3 species), Solanaceae (2 species), Amaranthaceae (15 species), Leguminosae (10 species), Polygonaceae (7 species), Malvaceae(4 species), Convolvulaceae (7 species), Brassicaceae (4 species) and Chenopodiaceae (4 species), From these, 25 species of quarantine weeds belonging to 5 families were present in high abundance.[Conclusion] American sorghum carried a great deal of seeds of weeds from diverse species, many of them being quarantine weeds. Therefore, more attention to these imports should be paid to strengthen the quarantine process and monitoring of American sorghum to prevent weed introduction into China and protect the environment.