Plant replacement control is an effective method to control weeds by using the growth advantage of one or more native plants. This method has been widely used to obtain economic and ecological benefits. This paper briefly introduces the status of research and application of replacement technology for three weeds in China. It summarizes the technical pattern and control effects of biological blocking and repair of the spreading and damage caused by Ambrosia artemisiifolia L. and Eupatorium adenophora L. and Flaveria bidentis (L.) Kuntze. We discuss the direction and key points of future research in this area.