[Background] With the unique geographical conditions, and because of the more and more frequent border trade, similar climate and cropping systems in Guangxi and Vietnam, Guangxi Province has become one of the most threatened areas by the invasion of alien species in China.[Method] This paper analyzed the current status of the biological invasions in Guangxi via a background survey.[Result] There were 26 species of invasive animals, 18 species of microorganism and 21 species of weeds. Some harmful invasive species of high risk includes the chilifruit fly[Bactrocera latifrons (Hendel)], the cassava mealybug (Phenacoccus manihoti Matile-Ferrero), the solenopsis mealybug (Phenacoccus solenopsis Tinsley), the rice water weevil (Lissorhoptrus oryzophilus Kuschel), and the Cucumber green mottle mosaic virus. 38 potentially hazardous pests from Vietnam are listed.[Conclusion and significance] Risk of harmful invasive species to Guangxi aggravated, with further spread tendency. Comprehensive strategy about the invasive alien pest was proposed, which provided some ideas controlling the invasive alien pests in Guangxi Province.