【Background】 Cydia pomonella (L.) is a worldwide major fruit-boring pest of rosaceae family such as apples and pears. It has so far infested Xinjiang, Gansu, Heilongjiang， Ningxia, Inner Mongolia, Jilin, and Liaoning provinces, China. This pest is spreading towards the major apple production areas, which can result in a great threat to apple industry in China. CypoGV is considered the best biological agent to control codling moth (C. pomonella) in Europe and America. It is important to develop domestic CypoGV commercial agents to protect apple production in China. 【Method】 The virulence to neonate larvae were tested in laboratory and field bioassay using the mixtures of CypoGV-ZY with different Fe2O3 concentrations (3, 5, 7, 10, 12 mg·mL-1) treated with UV, and sunlight. 【Result】 The virulence and persistence of CypoGV-ZY were significant increased when mixed with 7 mg·mL-1 Fe2O3 in both bioassays. It also enhanced CypoGV-ZY adaptability to strong UV and sunlight. Compared to control of CypoGV-ZY, mortality rate increased 53.88% and 96.64%, in laboratory and field bioassay, respectively. 【Conclusion and significance】 The virulence and persistence of CypoGV-ZY were markedly enhanced by adding low dose of Fe2O3, which showed that this compound was a proper candidate adjuvant for CypoGV-ZY. The results will provide the basis for commercial production of CypoGV-ZY.