With the progress and development of modern science and technology, the promotion and application of genetical modification (GM technology) has become a reality in many aspects of our life. For this reason, the GM technology and its safety have gradually become a great public concern. The changes of public opinion on GM could reflect the acceptance and knoweldge of GM technology. Public acceptance generates a benign environment for the development of GM technology. This article displayed and analyzed typical international public opinion events and global public opinion situation concerning the GM technology. Chinese public opinion on GM showed the following characteristics: network based, spreading widely, using safety slogans on both sides (supporters and opposers), emphasizing the uncertainty of the technology. In order to increase the level of articulation of the Chinese public opinion on GM in this article we suggest: (1) establishing information disclosure platform; (2) diversifying the methods of knowledge publicity; (3) strengthening GMO safety regulation; (4) setting up monitoring platform for public opinion on GM.