Transgenic technology can break species barriers and directly improve special characters of different crops. It is of great potential in assuring quality of agricultural products, especially in increasing grain yield, saving water, enhancing efficiency and environment pollution. On the other side, transgenic technology poses potential risks, the safety of genetically modified organisms (GMOs) has gained great public concern. This paper introduces current safety administration of agricultural GMOs in China, including regulation system, safety assessment system and safety supervision system. Hopefully, people could better understand the knowledge of agricultural GMO in China through this paper.