【Background】Golden apple snail (Pomacea canaliculata) was included in the first list of important invasive alien species in China. Previous studies have focused on the biological characterization, agricultural and integrated controls, and the effects of starvation on the species. Few studies have been conducted on the organ-surface impairment under starvation as a way to control the species. This is the focus of this study. 【Method】The responses of the survival and oviposition of P.canaliculata to starvation stress were observed and impairment of its head and liver tissues were measured by the technique of scanning electron microscope (SEM). 【Result】The results showed that more than 90% of snails could survive without food for 25 days. The number of egg mass of the starvation treatment group was 4 after 25 days, significantly lower than that of the control group (24.33) with food. Snail spawning could not be found when they were in the starvation treatment for over 12 days. Moreover, after the snails were starved for 25 days, the heads were shrinked and stacked with erosed floccule, the livers appeared a loose spiral structure with different shades of cracks and eroded damage. 【Conclusion and significance】Short-time starvation (25 days) has little effect on survival of P.canaliculata, but its spawning is significantly affected, and the tissue surface of their heads and livers have showed obvious injuries. These findings would provide some references for studying invasion mechanism and controlling of P.canaliculata.