Pomacea canaliculata is defined as an invasive species， because it has a strong environmental adaptability. P.canaliculata blooms in tropical, subtropical regions and causes ecological damage. All regions of the world have taken various measures to eliminate P.canaliculata but they have usually been ineffective. Because P.canaliculata has a strong resistance, it could tolerant extreme high temperature of 39 ℃ and a long time drought of 14 days. In addition, P.canaliculata also can resist pH 4.5~9.4 acidbase erosion and kinds of threatens of chemicals, bacteria and parasites. The article reviews relevant research on resistance or tolerance in P.canaliculata against physical, chemical and biological factors. The environmental factors induce physiological changes in P.canaliculata, including metabolic pathways, the accumulation of sugars and amino acids. P.canaliculata can also adapt to adversity by behavioural changes and adjust their reproductive strategy.