With faster economic development and globalization, exotic species invasion has been one of the most important factors that can affect national safety. As numerous exoticspecies were introduced deliberately or unconsciously, China has become one of the most threatened countries by alien species invasion. Although nonnative species have exerted dramatic environmental and socioeconomic effects, many countries and international societies are still trying to actively workon strategies to control invasion. This also includes the need to strengthening regulations to ensure national and international biosafety. Unfortunately, relevant laws and regulations cannot keep pace with such phenomenon as invasion of exotic species. In this paper, we reviewed the current situation of the exotic species in China as well as the related laws and regulations. We pointed out that exotic species invasion happens in various ecosystems, and revealed the "Bi-misplacement Phenomena", i.e., the misplacement between nature and economy, and the misplacement between ecological system and district division, resulted by the differences between district divisions and ecological systems. In addition, we analyzed the current management system for exotic invasive species in China and future development trends in this regard. We actively searched for invasive species management strategies for China under international venues, and proposed a law for invasion of exotic species that can be related to Chinese national jurisdiction system to promote research, administration and education through cooperation of different departments. We proposed that such management strategies should emphasize prevention.