【Background】Aleurodicus dispersus Russell, a destructive invasive pest was first found in Hainan, China, in April 2006. Botanical insecticides have long been suggested as attractive alternatives to synthetic ones for pest management because of their high potency, efficacy and more ecofriendly nature. 【Method】The spraying and film contact methods were used to measure the toxicity of nine botanical insecticides and their mixture against A.dispersus. 【Result】The maximum mortality of adults was recorded for pyrethrum and rotenone with LC50at 24 h being 2.56 mg·L-1and 34.15 mg·L-1, respectively. These were followed by azadirachtin (24 h LC50being 158.36 mg·L-1) and bitter melon leaf extracts (24 h LC 50 being 311.02 mg·L-1). Pyrethrum showed significant insecticidal action to the eggs and nymphs of A.dispersus with 24 h LC50 being 77.39 mg·L-1and 61.42 mg·L-1, respectively. Bioassay results indicated that mixed azadirachtin or rotenone with pyrethrum (1∶1) exhibited a significant synergism against A.dispersus, and their cotoxicity coefficient (CTC) were 193.11 and 224.35, respectively. 【Conclusion and significance】Several of the examined botanical pesticides showed potential to control A.dispersus. The mixture of azadirachtin or rotenone with pyrethrum could not only have synergism but also delay the resistance of A.dispersus.